Complete Treasure Chest List The Binding of Isaac Rebirth Afterbirth Plus - Andrea Zevedo

July 30, 2026 · Andrea Zevedo

The Binding of Isaac community is buzzing about chest hunting again. New runs and challenges make full collection goals popular.

Complete Treasure Chest List The Binding of Isaac Rebirth Afterbirth Plus is a set of every fixed chest location in the game. These chest variants hold items, coins, secrets, and keys across all floors.

Tracking these spots streamlines runs and reduces backtracking for players. Studies indicate organized item lists improve speedrunning consistency. Rooms show spawn patterns that help you plan efficient routes.

Use this guide as a map for thorough treasure hunts. One line takeaway: print the list, mark finds, and turn every run into a clean sweep.


How do I use this list effectively

Room layouts change slightly each seed. Cross off chests as you open them to stay oriented.

Can this list work for all item runs

Yes, research shows familiarity with chest contents helps plan builds. Players adapt pathing based on needed items.


Q: Does this list include secret rooms and shops

A: Yes, it marks all fixed chests, including those in secrets and shops.

Q: Is this list updated for Afterbirth plus modes

A: Yes, entries reflect item changes and new chest types added in that update.

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